And we're off to the races for AY 2011-2012!
We'll meet Tuesday, Sept. 27, 12:15 in Room E6519.
Many thanks to Elizabeth Ables of the Drummond-Barbosa lab for kicking us off.
She'll be presenting:
Loss of lysine specific demethylase 1 nonautonomously causes stem cell tumors in the Drosophila ovary
S. Eliazer, N.A. Shalaby, and M. Buszczak
PNAS 2011, 108:7032
She says, "I chose this paper because it describes an intriguing role for epigenetic modifiers, specifically the conserved histone demethylase Lsd1, functions (1) during development to regulate the size of the Drosophila germline stem cell (GSC) niche, and (2) in adult somatic tissue adjacent to the GSCs to limit the production of niche-specific signals that maintain GSCs. Cell autonomous epigenetic control of GSCs has been demonstrated by several labs (including the [Erika] Matunis lab), but to my knowledge, this is the the first report demonstrating that epigenetic modifications also control somatic niche cell development and function."
Thursday, September 22, 2011
Subscribe to:
Posts (Atom)