When and where: Room E6519, Tuesday, April 26, 12:15 PM
Andrew Wolfe will be presenting -- and I'm really excited about the paper he picked:
Endocrine regulation of male fertility by the skeleton
Cell 144:796-809
Oury et al.
Gerard Karsenty website at Columbia
Commentary on this paper
... as this paper is one that caught my eye, and I posted it with suggestions for a "DIY" journal club to replace the March 22 one. It's also a paper that some outside the reproductive biology community are noticing and have asked me about -- so it catching some attention. We'll discuss to determine if it's truth or fiction, or somewhere in between!
Wednesday, April 20, 2011
Thursday, April 7, 2011
April 12, 2011 journal club
When and where: Room W2303, Tuesday, April 12, 12:15 PM
Shiying Jin of the Zirkin lab will present:
Protein tyrosine kinase WEE1B is essential for metaphase II exit in mouse oocytes
Oh JS, Susor A, and Conti M [Marco Conti's UCSF webpage]
Science 2011, ePub ahead of print (DOI: 10.1126/science.1199211)
This paper presents the interesting finding that (as the abstract states), "... exit from metaphase requires not only a proteolytic degradation of cyclin B, but also the inhibitory phosphorylation of Cdc2 by Wee1B," as well as reveals an additional role for Calcium/Calmodulin-dependent kinase II (CaMKII) in the egg-to-embryo transition. This work also extends what we know about WEE1B functions in oocytes, complementing previous work of the Conti lab on the role of WEE1B in prophase I arrest (Curr Biol, 15:1670).
Shiying Jin of the Zirkin lab will present:
Protein tyrosine kinase WEE1B is essential for metaphase II exit in mouse oocytes
Oh JS, Susor A, and Conti M [Marco Conti's UCSF webpage]
Science 2011, ePub ahead of print (DOI: 10.1126/science.1199211)
This paper presents the interesting finding that (as the abstract states), "... exit from metaphase requires not only a proteolytic degradation of cyclin B, but also the inhibitory phosphorylation of Cdc2 by Wee1B," as well as reveals an additional role for Calcium/Calmodulin-dependent kinase II (CaMKII) in the egg-to-embryo transition. This work also extends what we know about WEE1B functions in oocytes, complementing previous work of the Conti lab on the role of WEE1B in prophase I arrest (Curr Biol, 15:1670).
Labels:
cell cycle,
egg,
egg activation,
fertilization,
meetings,
oocyte/egg
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